MersV1, Main, Exploration, bibRecord, 000B31

Untargeted metabolite analysis-based UHPLC-Q-TOF-MS reveals significant enrichment of p-hydroxybenzyl dimers of citric acids in fresh beige-scape Gastrodia elata (Wutianma).

Identifieur interne : 000B31 ( Main/Exploration ); précédent : 000B30; suivant : 000B32

Untargeted metabolite analysis-based UHPLC-Q-TOF-MS reveals significant enrichment of p-hydroxybenzyl dimers of citric acids in fresh beige-scape Gastrodia elata (Wutianma).

Source :

Journal of pharmaceutical and biomedical analysis [ 1873-264X ] ; 2017.

RBID : pubmed:28380386

Descripteurs français

English descriptors

KwdEn :
- Chromatography, High Pressure Liquid, Citric Acid, Dimerization, Gastrodia, Mass Spectrometry, Plant Extracts, Plant Tubers, Plants, Medicinal.
MESH :
- chemical : Citric Acid, Plant Extracts.
- Chromatography, High Pressure Liquid, Dimerization, Gastrodia, Mass Spectrometry, Plant Tubers, Plants, Medicinal.

Abstract

In order to comprehensively elucidate the chemical biosynthesis process of the beige-scape Gastrodia elata Blume (Wutianma) as a traditional herbal medicines, the untargeted analysis-based UHPLC-PDA-ESI-Q-TOF-MS reveals the metabolites ranging from the skeletons to novel dimers of citric acids in fresh and dried immature/mature stem tubers. Interestingly, two novel types of dimers for citric acids with the anhydride groups at sn-1 and/or sn-5 were discovered in fresh samples. Moreover, the classical mono- versus novel di-mers, and the aglycons versus the glycosides could be easily discriminated by signature fragmentation patterns and some novel adduct ions. The heat map of contents demonstrated more p-hydroxybenzyl metabolites than gastroxyl ones were determined in fresh Wutianma revealing a significant specificity with the lack of the sufficient gastrodin and gastroxyl products in biosynthetic pathway.

DOI: 10.1016/j.jpba.2017.03.055
PubMed: 28380386

Affiliations:

République populaire de Chine

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Untargeted metabolite analysis-based UHPLC-Q-TOF-MS reveals significant enrichment of p-hydroxybenzyl dimers of citric acids in fresh beige-scape Gastrodia elata (Wutianma).</title>
<author><name sortKey="Lai, Chang Jiang Sheng" sort="Lai, Chang Jiang Sheng" uniqKey="Lai C" first="Chang-Jiang-Sheng" last="Lai">Chang-Jiang-Sheng Lai</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China. Electronic address: laichangjiang44@126.com.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yuan, Yuan" sort="Yuan, Yuan" uniqKey="Yuan Y" first="Yuan" last="Yuan">Yuan Yuan</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liu, Da Hui" sort="Liu, Da Hui" uniqKey="Liu D" first="Da-Hui" last="Liu">Da-Hui Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>College of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>College of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065</wicri:regionArea>
<wicri:noRegion>430065</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kang, Chuan Zhi" sort="Kang, Chuan Zhi" uniqKey="Kang C" first="Chuan-Zhi" last="Kang">Chuan-Zhi Kang</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Yu" sort="Zhang, Yu" uniqKey="Zhang Y" first="Yu" last="Zhang">Yu Zhang</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zha, Liangping" sort="Zha, Liangping" uniqKey="Zha L" first="Liangping" last="Zha">Liangping Zha</name>
<affiliation wicri:level="1"><nlm:affiliation>College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012</wicri:regionArea>
<wicri:noRegion>230012</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kang, Liping" sort="Kang, Liping" uniqKey="Kang L" first="Liping" last="Kang">Liping Kang</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chen, Tong" sort="Chen, Tong" uniqKey="Chen T" first="Tong" last="Chen">Tong Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nan, Tie Gui" sort="Nan, Tie Gui" uniqKey="Nan T" first="Tie-Gui" last="Nan">Tie-Gui Nan</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hao, Qing Xiu" sort="Hao, Qing Xiu" uniqKey="Hao Q" first="Qing-Xiu" last="Hao">Qing-Xiu Hao</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Huang, Lu Qi" sort="Huang, Lu Qi" uniqKey="Huang L" first="Lu-Qi" last="Huang">Lu-Qi Huang</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China. Electronic address: huangluqi01@126.com.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:28380386</idno>
<idno type="pmid">28380386</idno>
<idno type="doi">10.1016/j.jpba.2017.03.055</idno>
<idno type="wicri:Area/PubMed/Corpus">000D32</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D32</idno>
<idno type="wicri:Area/PubMed/Curation">000D32</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000D32</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000A71</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000A71</idno>
<idno type="wicri:Area/Ncbi/Merge">001999</idno>
<idno type="wicri:Area/Ncbi/Curation">001999</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001999</idno>
<idno type="wicri:Area/Main/Merge">000B34</idno>
<idno type="wicri:Area/Main/Curation">000B31</idno>
<idno type="wicri:Area/Main/Exploration">000B31</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Untargeted metabolite analysis-based UHPLC-Q-TOF-MS reveals significant enrichment of p-hydroxybenzyl dimers of citric acids in fresh beige-scape Gastrodia elata (Wutianma).</title>
<author><name sortKey="Lai, Chang Jiang Sheng" sort="Lai, Chang Jiang Sheng" uniqKey="Lai C" first="Chang-Jiang-Sheng" last="Lai">Chang-Jiang-Sheng Lai</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China. Electronic address: laichangjiang44@126.com.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Yuan, Yuan" sort="Yuan, Yuan" uniqKey="Yuan Y" first="Yuan" last="Yuan">Yuan Yuan</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liu, Da Hui" sort="Liu, Da Hui" uniqKey="Liu D" first="Da-Hui" last="Liu">Da-Hui Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>College of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>College of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065</wicri:regionArea>
<wicri:noRegion>430065</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kang, Chuan Zhi" sort="Kang, Chuan Zhi" uniqKey="Kang C" first="Chuan-Zhi" last="Kang">Chuan-Zhi Kang</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhang, Yu" sort="Zhang, Yu" uniqKey="Zhang Y" first="Yu" last="Zhang">Yu Zhang</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zha, Liangping" sort="Zha, Liangping" uniqKey="Zha L" first="Liangping" last="Zha">Liangping Zha</name>
<affiliation wicri:level="1"><nlm:affiliation>College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012</wicri:regionArea>
<wicri:noRegion>230012</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kang, Liping" sort="Kang, Liping" uniqKey="Kang L" first="Liping" last="Kang">Liping Kang</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chen, Tong" sort="Chen, Tong" uniqKey="Chen T" first="Tong" last="Chen">Tong Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nan, Tie Gui" sort="Nan, Tie Gui" uniqKey="Nan T" first="Tie-Gui" last="Nan">Tie-Gui Nan</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Hao, Qing Xiu" sort="Hao, Qing Xiu" uniqKey="Hao Q" first="Qing-Xiu" last="Hao">Qing-Xiu Hao</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Huang, Lu Qi" sort="Huang, Lu Qi" uniqKey="Huang L" first="Lu-Qi" last="Huang">Lu-Qi Huang</name>
<affiliation wicri:level="1"><nlm:affiliation>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700, PR China. Electronic address: huangluqi01@126.com.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, State Key Laboratory Breeding Base of Dao-di Herbs, Beijng, 100700</wicri:regionArea>
<wicri:noRegion>100700</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of pharmaceutical and biomedical analysis</title>
<idno type="eISSN">1873-264X</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chromatography, High Pressure Liquid</term>
<term>Citric Acid</term>
<term>Dimerization</term>
<term>Gastrodia</term>
<term>Mass Spectrometry</term>
<term>Plant Extracts</term>
<term>Plant Tubers</term>
<term>Plants, Medicinal</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Acide citrique</term>
<term>Chromatographie en phase liquide à haute performance</term>
<term>Dimérisation</term>
<term>Extraits de plantes</term>
<term>Gastrodia</term>
<term>Plantes médicinales</term>
<term>Spectrométrie de masse</term>
<term>Tubercules</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Citric Acid</term>
<term>Plant Extracts</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Chromatography, High Pressure Liquid</term>
<term>Dimerization</term>
<term>Gastrodia</term>
<term>Mass Spectrometry</term>
<term>Plant Tubers</term>
<term>Plants, Medicinal</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Acide citrique</term>
<term>Chromatographie en phase liquide à haute performance</term>
<term>Dimérisation</term>
<term>Extraits de plantes</term>
<term>Gastrodia</term>
<term>Plantes médicinales</term>
<term>Spectrométrie de masse</term>
<term>Tubercules</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">In order to comprehensively elucidate the chemical biosynthesis process of the beige-scape Gastrodia elata Blume (Wutianma) as a traditional herbal medicines, the untargeted analysis-based UHPLC-PDA-ESI-Q-TOF-MS reveals the metabolites ranging from the skeletons to novel dimers of citric acids in fresh and dried immature/mature stem tubers. Interestingly, two novel types of dimers for citric acids with the anhydride groups at sn-1 and/or sn-5 were discovered in fresh samples. Moreover, the classical mono- versus novel di-mers, and the aglycons versus the glycosides could be easily discriminated by signature fragmentation patterns and some novel adduct ions. The heat map of contents demonstrated more p-hydroxybenzyl metabolites than gastroxyl ones were determined in fresh Wutianma revealing a significant specificity with the lack of the sufficient gastrodin and gastroxyl products in biosynthetic pathway.</div>
</front>
</TEI>
<affiliations><list><country><li>République populaire de Chine</li>
</country>
</list>
<tree><country name="République populaire de Chine"><noRegion><name sortKey="Lai, Chang Jiang Sheng" sort="Lai, Chang Jiang Sheng" uniqKey="Lai C" first="Chang-Jiang-Sheng" last="Lai">Chang-Jiang-Sheng Lai</name>
</noRegion>
<name sortKey="Chen, Tong" sort="Chen, Tong" uniqKey="Chen T" first="Tong" last="Chen">Tong Chen</name>
<name sortKey="Hao, Qing Xiu" sort="Hao, Qing Xiu" uniqKey="Hao Q" first="Qing-Xiu" last="Hao">Qing-Xiu Hao</name>
<name sortKey="Huang, Lu Qi" sort="Huang, Lu Qi" uniqKey="Huang L" first="Lu-Qi" last="Huang">Lu-Qi Huang</name>
<name sortKey="Kang, Chuan Zhi" sort="Kang, Chuan Zhi" uniqKey="Kang C" first="Chuan-Zhi" last="Kang">Chuan-Zhi Kang</name>
<name sortKey="Kang, Liping" sort="Kang, Liping" uniqKey="Kang L" first="Liping" last="Kang">Liping Kang</name>
<name sortKey="Liu, Da Hui" sort="Liu, Da Hui" uniqKey="Liu D" first="Da-Hui" last="Liu">Da-Hui Liu</name>
<name sortKey="Nan, Tie Gui" sort="Nan, Tie Gui" uniqKey="Nan T" first="Tie-Gui" last="Nan">Tie-Gui Nan</name>
<name sortKey="Yuan, Yuan" sort="Yuan, Yuan" uniqKey="Yuan Y" first="Yuan" last="Yuan">Yuan Yuan</name>
<name sortKey="Zha, Liangping" sort="Zha, Liangping" uniqKey="Zha L" first="Liangping" last="Zha">Liangping Zha</name>
<name sortKey="Zhang, Yu" sort="Zhang, Yu" uniqKey="Zhang Y" first="Yu" last="Zhang">Yu Zhang</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B31 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000B31 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    MersV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:28380386
   |texte=   Untargeted metabolite analysis-based UHPLC-Q-TOF-MS reveals significant enrichment of p-hydroxybenzyl dimers of citric acids in fresh beige-scape Gastrodia elata (Wutianma).
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:28380386" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a MersV1

This area was generated with Dilib version V0.6.33.
Data generation: Mon Apr 20 23:26:43 2020. Site generation: Sat Mar 27 09:06:09 2021

Serveur d'exploration MERS

Untargeted metabolite analysis-based UHPLC-Q-TOF-MS reveals significant enrichment of p-hydroxybenzyl dimers of citric acids in fresh beige-scape Gastrodia elata (Wutianma).

Untargeted metabolite analysis-based UHPLC-Q-TOF-MS reveals significant enrichment of p-hydroxybenzyl dimers of citric acids in fresh beige-scape Gastrodia elata (Wutianma).

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration MERS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.